To reach their conclusions, Bloomfield et al. selected 15 randomized patients to receive a 600mg dose of oral CBD or a placebo. They received the medication in identical capsules on different days while researchers used MR imaging to measure blood oxygen levels in their brains.
CBD boosted flow in the hippocampus and the orbitofrontal cortex, part of the larger prefrontal cortex which is used in planning and decision-making, the authors noted. Interestingly, blood flow was unaffected in the medial temporal lobe, which is largely made up of the hippocampus.
Bloomfield and colleagues pointed out that their research was limited by only using a single dose of CBD in healthy patients and may not translate to repeated use.
Aside from this, they believe their results could be an “important discovery” for memory conditions, such as post-traumatic stress disorder and improving targeted-therapy approaches.
“If replicated, these results could lead to further research across a range of conditions characterized by changes in how the brain processes memories, including Alzheimer’s disease, where there are defects in the control of blood control flow, along with schizophrenia and post-traumatic stress disorder,” Bloomfield said.
Read the entire study here.